FaCD Online Syndrome Fact Sheet
Last updated: 04 Apr 2008
Name: Familial Multiple Acral Mucinous Fibrokeratomas
Mode of Inheritance: AD? / multifact?
Tumor featuresmucinous fibrokeratomas
Comment
Moulin et al.[1] reported a woman, son and granddaughter who had developed multiple verrucous lesions of the hands and fingers, starting at the age of 10-12 years. Histology of the lesions showed hyperkeratotic, papillomatous, vascular fibromas with mucinous deposits, some showed acanthosis and myxomatous changes. Based on differences in histology and clinical presentation, the authors ruled out tuberous sclerosis, acral persistent papular mucinosis, acrokeratosis verruciformis, papular mucinosis, punctate or papular keratoderma and hereditary progressive mucinous histiocytosis.
References
[1] Moulin G, Balme B, Thomas L. Familial multiple acral mucinous fibrokeratomas. J Am Acad Dermatol 1998; 38(6 part1):999-1001.
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