FaCD Online Syndrome Fact Sheet

Last updated: 04 Apr 2008

Name: Familial Multiple Acral Mucinous Fibrokeratomas

Mode of Inheritance: AD? / multifact?

Tumor features

mucinous fibrokeratomas

Comment

Moulin et al.[1] reported a woman, son and granddaughter who had developed multiple verrucous lesions of the hands and fingers, starting at the age of 10-12 years. Histology of the lesions showed hyperkeratotic, papillomatous, vascular fibromas with mucinous deposits, some showed acanthosis and myxomatous changes. Based on differences in histology and clinical presentation, the authors ruled out tuberous sclerosis, acral persistent papular mucinosis, acrokeratosis verruciformis, papular mucinosis, punctate or papular keratoderma and hereditary progressive mucinous histiocytosis.

References

[1] Moulin G, Balme B, Thomas L. Familial multiple acral mucinous fibrokeratomas. J Am Acad Dermatol 1998; 38(6 part1):999-1001.